"Patients usually have many years of chronic constipation and manage their condition by the use of laxatives, enemas and even manual evacuation and de-impaction. They, therefore, either present with chronic constipation or with acute decompensation with acute large bowel obstruction 2,3."
"Similar to usual Hirschsprung disease, adult Hirschsprung disease is characterised by aganglionosis (absence of ganglion cells) in the distal colon and rectum 3. There is typically short or ultrashort segment disease 3."