"CT "
"mucoid impaction results in a bronchocoele, the finger in glove sign"
"centrilobular nodular opacities."
"immediate skin reactivity to Aspergillus antigen (elevated IgG and/or IgE against A. fumigatus)"
"ASPER criteria include asthma/atopy history, serum IgG or IgE against Aspergillus spp., proximal (central) bronchiectasis, IgE levels >1000ng/mL, and reactive skin test."
"Allergic bronchopulmonary aspergillosis is the result of hypersensitivity towards Aspergillus spp (esp fumigatus) which grows within the lumen of the bronchi, without invasion. The hypersensitivity initially causes bronchospasm and bronchial wall oedema, which is IgE-mediated. Ultimately, there is bronchial wall damage with loss of muscle and bronchial wall cartilage resulting in bronchiectasis (typically central bronchiectasis) 7. Both types I and III allergic reactions have been implicated 4."
"elevated Aspergillus-specific IgE"
"elevated precipitating IgG against Aspergillus"
"Treatment of allergic bronchopulmonary aspergillosis is difficult due to the ubiquity of Aspergillus in the environment. The main focus of treatment revolves around 8:"
"eradicating Aspergillus from the airway: antifungal agents, e.g. ketoconazole"
"ASPER criteria include asthma/atopy history, serum IgG or IgE against Aspergillus spp., proximal (central) bronchiectasis, IgE levels >1000ng/mL, and reactive skin test."
Expected headings
"CT "
"this may give a Y, V or toothpaste-like configuration"