"Extraction and retention "
"13NH3 is a PET tracer used for studies of myocardial perfusion imaging. It is produced in a cyclotron by proton irradiation of the enriched water of the oxygen-16. Ammonia (N-13) is administered intravenously, at a dose of 10-20 mCi (370-740 Mbq) in adults; its physical half-life is 10 minutes."
"Ammonia, at physiological pH, is found in its cationic form, 13NH4+ (ammonium ion); it is, therefore, probable that it passes the cell membrane of the myocyte through the sodium-potassium pump (Na+/K+) active transport mechanism. Inside the cell, it is then converted, together with glutamic acid, into glutamine (N-13)."
Expected headings
"Extraction and retention "
"13NH3 is a PET tracer used for studies of myocardial perfusion imaging. It is produced in a cyclotron by proton irradiation of the enriched water of the oxygen-16. Ammonia (N-13) is administered intravenously, at a dose of 10-20 mCi (370-740 Mbq) in adults; its physical half-life is 10 minutes."
"Ammonia, at physiological pH, is found in its cationic form, 13NH4+ (ammonium ion); it is, therefore, probable that it passes the cell membrane of the myocyte through the sodium-potassium pump (Na+/K+) active transport mechanism. Inside the cell, it is then converted, together with glutamic acid, into glutamine (N-13)."