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Lint: atypical-teratoidrhabdoid-tumour

Number Comparisons
error

"The vast majority (~95%) of AT/RTs have inactivation of both copies of SMARCB1 (also known as INI1, BAF47 or hSNF5). In a small minority of cases (< 5%) it is SMARCA4 (also known as BRG1) that is inactivated 13."

Line 9:151 · There should never be a space after less and greater than signs.
Strong List Colon Position
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"T1: iso- to slightly hyperintense to grey matter (haemorrhagic areas can be more hyperintense)"

Line 50:8 · When enboldening an intro, the colon should not be bold. '<strong>T1:</strong> iso'

"T2: generally hyperintense (haemorrhagic areas can be hypointense)"

Line 51:8 · When enboldening an intro, the colon should not be bold. '<strong>T2:</strong> generally'

"T1 C+ (Gd): heterogeneous enhancement"

Line 52:8 · When enboldening an intro, the colon should not be bold. '<strong>T1 C+ (Gd):</strong> heterogeneous'
Citation Preceding Space
error

"lower ADC14"

Line 80:17 · Citations must have a preceding space, e.g. needs evidence <sup>2</sup>. '<sup>14</sup>'

"indistinctive tumour margin14"

Line 81:35 · Citations must have a preceding space, e.g. needs evidence <sup>2</sup>. '<sup>14</sup>'

"absence of "tumour central vein" sign14"

Line 82:45 · Citations must have a preceding space, e.g. needs evidence <sup>2</sup>. '<sup>14</sup>'
Acronyms
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"Atypical teratoid/rhabdoid tumours (AT/RT) are uncommon WHO grade 4 tumours, which in the vast majority of cases occurs in young children less than two years of age. It most frequently presents as a posterior fossa mass. AT/RT often resembles medulloblastoma by imaging and even H&E microscopy, and the diagnosis requires cytogenetic analysis of the tissue."

Line 1:65 · 'AT' has no definition. Spell it out if it's unfamiliar to the audience.

"Atypical teratoid/rhabdoid tumours (AT/RT) are uncommon WHO grade 4 tumours, which in the vast majority of cases occurs in young children less than two years of age. It most frequently presents as a posterior fossa mass. AT/RT often resembles medulloblastoma by imaging and even H&E microscopy, and the diagnosis requires cytogenetic analysis of the tissue."

Line 1:68 · 'RT' has no definition. Spell it out if it's unfamiliar to the audience.

"Atypical teratoid/rhabdoid tumours (AT/RT) are uncommon WHO grade 4 tumours, which in the vast majority of cases occurs in young children less than two years of age. It most frequently presents as a posterior fossa mass. AT/RT often resembles medulloblastoma by imaging and even H&E microscopy, and the diagnosis requires cytogenetic analysis of the tissue."

Line 1:273 · 'AT' has no definition. Spell it out if it's unfamiliar to the audience.

"Atypical teratoid/rhabdoid tumours (AT/RT) are uncommon WHO grade 4 tumours, which in the vast majority of cases occurs in young children less than two years of age. It most frequently presents as a posterior fossa mass. AT/RT often resembles medulloblastoma by imaging and even H&E microscopy, and the diagnosis requires cytogenetic analysis of the tissue."

Line 1:276 · 'RT' has no definition. Spell it out if it's unfamiliar to the audience.

"AT/RTs typically present in very young children (median age is less than 2-3 years 2,13)."

Line 3:4 · 'AT' has no definition. Spell it out if it's unfamiliar to the audience.

"Rhabdoid cells are the hallmark of AT/RT, but only comprise a fraction of the tumour and are not required for the diagnosis provided genetic of DNA-methylation changes are compatible (see below) 13."

Line 6:39 · 'AT' has no definition. Spell it out if it's unfamiliar to the audience.

"Rhabdoid cells are the hallmark of AT/RT, but only comprise a fraction of the tumour and are not required for the diagnosis provided genetic of DNA-methylation changes are compatible (see below) 13."

Line 6:42 · 'RT' has no definition. Spell it out if it's unfamiliar to the audience.

"The vast majority (~95%) of AT/RTs have inactivation of both copies of SMARCB1 (also known as INI1, BAF47 or hSNF5). In a small minority of cases (< 5%) it is SMARCA4 (also known as BRG1) that is inactivated 13."

Line 9:32 · 'AT' has no definition. Spell it out if it's unfamiliar to the audience.

"Additionally, AT/RTs can be divided into three subgroups according to DNA-methylation profiling: AT/RT-SHH, AT/RT-TYR, and AT/RT-MYC 13."

Line 10:18 · 'AT' has no definition. Spell it out if it's unfamiliar to the audience.

"Additionally, AT/RTs can be divided into three subgroups according to DNA-methylation profiling: AT/RT-SHH, AT/RT-TYR, and AT/RT-MYC 13."

Line 10:108 · 'AT' has no definition. Spell it out if it's unfamiliar to the audience.

"Additionally, AT/RTs can be divided into three subgroups according to DNA-methylation profiling: AT/RT-SHH, AT/RT-TYR, and AT/RT-MYC 13."

Line 10:111 · 'RT-SHH' has no definition. Spell it out if it's unfamiliar to the audience.

"Additionally, AT/RTs can be divided into three subgroups according to DNA-methylation profiling: AT/RT-SHH, AT/RT-TYR, and AT/RT-MYC 13."

Line 10:119 · 'AT' has no definition. Spell it out if it's unfamiliar to the audience.

"Additionally, AT/RTs can be divided into three subgroups according to DNA-methylation profiling: AT/RT-SHH, AT/RT-TYR, and AT/RT-MYC 13."

Line 10:122 · 'RT-TYR' has no definition. Spell it out if it's unfamiliar to the audience.

"Additionally, AT/RTs can be divided into three subgroups according to DNA-methylation profiling: AT/RT-SHH, AT/RT-TYR, and AT/RT-MYC 13."

Line 10:134 · 'AT' has no definition. Spell it out if it's unfamiliar to the audience.

"Additionally, AT/RTs can be divided into three subgroups according to DNA-methylation profiling: AT/RT-SHH, AT/RT-TYR, and AT/RT-MYC 13."

Line 10:137 · 'RT-MYC' has no definition. Spell it out if it's unfamiliar to the audience.

"EMA: positive"

Line 15:11 · 'EMA' has no definition. Spell it out if it's unfamiliar to the audience.

"NAA: decreased"

Line 57:11 · 'NAA' has no definition. Spell it out if it's unfamiliar to the audience.

"Leptomeningeal seeding has been described in up to 15-30% of cases and so post-contrast imaging of the entire neuroaxis should be considered in suspected AT/RTs."

Line 65:158 · 'AT' has no definition. Spell it out if it's unfamiliar to the audience.

"Surgery with debulking can be offered in some cases. Tumours can demonstrate leptomeningeal dissemination. Clinically AT/RTs have a much poorer prognosis than medulloblastomas, with little if any response to chemotherapy and death usually occurring within a year of diagnosis."

Line 67:122 · 'AT' has no definition. Spell it out if it's unfamiliar to the audience.

"embryonal tumour with multilayered rosettes particularly for supratentorial AT/RTs"

Line 73:91 · 'AT' has no definition. Spell it out if it's unfamiliar to the audience.

"haemorrhage is much less frequently seen than in AT/RTs 6"

Line 79:57 · 'AT' has no definition. Spell it out if it's unfamiliar to the audience.

"CNS tumour with BCOR internal tandem duplication"

Line 85:27 · 'BCOR' has no definition. Spell it out if it's unfamiliar to the audience.
List Caps
warning

"Cho: elevated"

Line 56:11 · In general, we don't start a list item with a capital letter. Exceptions are proper nouns.
Headings Valid
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Expected headings

  • H1 Terminology
  • H1 Usage
  • H1 Epidemiology
  • H2 Risk factors
  • H2 Associations
  • H1 Clinical presentation
  • H2 Complications
  • H1 Diagnosis
  • H2 Diagnostic criteria
  • H2 Diagnostic clues
  • H1 Pathology
  • H2 Aetiology
  • H2 Location
  • H2 Classification
  • H2 Macroscopic appearance
  • H2 Microscopic appearance
  • H2 Immunophenotype
  • H2 Markers
  • H2 Genetics
  • H1 Radiographic features
  • H2 Plain radiograph
  • H2 Mammography
  • H2 Antenatal ultrasound
  • H2 Transoesophageal echocardiography
  • H2 Ultrasound
  • H2 CT
  • H3 Dual-energy CT
  • H2 Angiography (DSA)
  • H2 MRI
  • H2 CT/MRI
  • H2 Nuclear medicine
  • H3 PET-CT
  • H3 PET-MRI
  • H1 Radiology report
  • H1 Treatment and prognosis
  • H2 Complications
  • H1 History and etymology
  • H1 Differential diagnosis
  • H2 Clinical differential diagnosis
  • H1 Practical points
  • H1 See also

"Microscopic features"

Line 5:1 · "Microscopic features" is not a recognised heading for this article type.

"Location"

Line 21:1 · "Location" is under the wrong parent heading (found under "Radiographic features").
Oxford Comma
suggestion

"The vast majority (~95%) of AT/RTs have inactivation of both copies of SMARCB1 (also known as INI1, BAF47 or hSNF5). In a small minority of cases (< 5%) it is SMARCA4 (also known as BRG1) that is inactivated 13."

Line 9:98 · Use the Oxford comma in 'INI1, BAF47 or hSNF5'.