"The condition is largely restricted to the villages along the Danube river and its tributaries in Bosnia–Herzegovina, Bulgaria, Croatia, Romania and Serbia. It typically occurs in 2-5% of individuals after 15 years of living in the area and is believed to be due to ingestion of aristolochic acid, found in seeds of the Aristolochia clematitis plant 2."
"The condition is largely restricted to the villages along the Danube river and its tributaries in Bosnia–Herzegovina, Bulgaria, Croatia, Romania and Serbia. It typically occurs in 2-5% of individuals after 15 years of living in the area and is believed to be due to ingestion of aristolochic acid, found in seeds of the Aristolochia clematitis plant 2."
"The same condition was previously termed Chinese herbs nephropathy, when aristolochic acid-containing extracts were inadvertently added to slimming tablets in Brussels in 1990 2,3."
"Urothelial carcinomas in these patients are typically multiple and low grade, located within the renal pelvis or upper ureter 1. Findings are similar to sporadic urothelial carcinomas (thus please refer to UC of the renal pelvis, and UC of the ureter for further discussion)."
"Urothelial carcinomas in these patients are typically multiple and low grade, located within the renal pelvis or upper ureter 1. Findings are similar to sporadic urothelial carcinomas (thus please refer to UC of the renal pelvis, and UC of the ureter for further discussion)."
"The condition is largely restricted to the villages along the Danube river and its tributaries in Bosnia–Herzegovina, Bulgaria, Croatia, Romania and Serbia. It typically occurs in 2-5% of individuals after 15 years of living in the area and is believed to be due to ingestion of aristolochic acid, found in seeds of the Aristolochia clematitis plant 2."
"As these tumours are bilateral, multiple and of low grade, conservative management is the mainstay of treatment 1."
"There are presumably genetic reasons to explain why only a minority of patients living in endemic areas and consuming toxic levels of aristolochic acid develop the nephropathy and associated upper urinary tract urothelial carcinomas."