"Brucellosis is a global zoonotic infection secondary to any of the four Brucella spp. that infect humans. It can be focal or systemic but has a particular affinity for the musculoskeletal system."
"Various methods to detect IgM and/or IgG antibodies have been proposed, with some conflict in the literature regarding which is optimal for diagnosis. The Rose Bengal test, serum agglutination test, Coombs test, lateral flow immunochromatography assay, a fluorescence polarisation assay, indirect ELISA assays, and the immunocapture BrucellaCapt test may be used independently or in combination to confirm Brucella infection 6."
"Brucella spp. are gram-negative coccobacilli, which are mostly spread animal-to-human via unpasteurised dairy products. A number of species can act as primary hosts to infect humans as secondary hosts. Four main species infect humans 1-4:"
"Brucella melitensis (camel, sheep)"
"Brucella suis (pigs)"
"Brucella abortus (cattle)"
"Brucella canis (dogs)"
"Rarely, the more recently discovered fifth and sixth species B. ceti and B. pinnipediae - found in marine mammals - have been isolated in the context of neurobrucellosis. The CDC has classified the Brucella abortus, canis, and suis species as "select agents" due to their potential to be aerosolised for bioterrorism purposes."
"Brucella is eponymously named in honour of the early investigatory work into disease pathogenesis performed by Scottish microbiologist Sir David Bruce (1855-1931), who was born in Melbourne, Australia 9."
"Of note, B. abortus is so named as it causes spontaneous abortion in the third trimester in cattle 7."
"Various methods to detect IgM and/or IgG antibodies have been proposed, with some conflict in the literature regarding which is optimal for diagnosis. The Rose Bengal test, serum agglutination test, Coombs test, lateral flow immunochromatography assay, a fluorescence polarisation assay, indirect ELISA assays, and the immunocapture BrucellaCapt test may be used independently or in combination to confirm Brucella infection 6."
"Brucella melitensis (camel, sheep)"
"Brucella suis (pigs)"
"Brucella abortus (cattle)"
"Brucella canis (dogs)"
"Various methods to detect IgM and/or IgG antibodies have been proposed, with some conflict in the literature regarding which is optimal for diagnosis. The Rose Bengal test, serum agglutination test, Coombs test, lateral flow immunochromatography assay, a fluorescence polarisation assay, indirect ELISA assays, and the immunocapture BrucellaCapt test may be used independently or in combination to confirm Brucella infection 6."