"Occasionally this entity forms part of a rare autosomal dominantly inherited syndrome, called familial calvarial doughnut lesions syndrome or calvarial doughnut lesions – bone fragility syndrome 3. This entity characterises by multiple calvarial doughnut lesions, with lumps on the head, many pathologic fractures, dental caries, undeveloped teeth, and elevated serum alkaline phosphatase (ALP) levels 3,6."
"Occasionally this entity forms part of a rare autosomal dominantly inherited syndrome, called familial calvarial doughnut lesions syndrome or calvarial doughnut lesions – bone fragility syndrome 3. This entity characterises by multiple calvarial doughnut lesions, with lumps on the head, many pathologic fractures, dental caries, undeveloped teeth, and elevated serum alkaline phosphatase (ALP) levels 3,6."
"Occasionally this entity forms part of a rare autosomal dominantly inherited syndrome, called familial calvarial doughnut lesions syndrome or calvarial doughnut lesions – bone fragility syndrome 3. This entity characterises by multiple calvarial doughnut lesions, with lumps on the head, many pathologic fractures, dental caries, undeveloped teeth, and elevated serum alkaline phosphatase (ALP) levels 3,6."
"MR reveals expansile diploic homogeneous well-perfused soft-tissue lesions low signal intensity in T2 WI due to the high content of fibrous tissue 3. There is a hypointense ringlike structure surrounding these lesions, which represents the sclerotic ring 3. The CT is best to see the calcified portion of the lesion 3."
Expected headings
"Microscopic features"
"Occasionally this entity forms part of a rare autosomal dominantly inherited syndrome, called familial calvarial doughnut lesions syndrome or calvarial doughnut lesions – bone fragility syndrome 3. This entity characterises by multiple calvarial doughnut lesions, with lumps on the head, many pathologic fractures, dental caries, undeveloped teeth, and elevated serum alkaline phosphatase (ALP) levels 3,6."
"These lesions may show central mesenchymal and fibrous tissue with clusters of foamy cells, usually with a nidus of irregular bone trabeculae and surrounding sclerotic cortical bone 1,3-6. There is no osteoblastic or osteoclastic proliferation; and no haemosiderin deposition, eosinophils, or inflammatory cells 1,3-5."
"MR reveals expansile diploic homogeneous well-perfused soft-tissue lesions low signal intensity in T2 WI due to the high content of fibrous tissue 3. There is a hypointense ringlike structure surrounding these lesions, which represents the sclerotic ring 3. The CT is best to see the calcified portion of the lesion 3."
"There is no evidence for intervention or surgical management of the disorder ref."
"These lesions may show central mesenchymal and fibrous tissue with clusters of foamy cells, usually with a nidus of irregular bone trabeculae and surrounding sclerotic cortical bone 1,3-6. There is no osteoblastic or osteoclastic proliferation; and no haemosiderin deposition, eosinophils, or inflammatory cells 1,3-5."