"The underlying pathogenesis is similar to classic antiphospholipid syndrome, but the severity of the disease is more severe 3. Due to the extent of the organ involvement, a systemic inflammatory response syndrome is usually present also. Precipitating factors may include infection, medication or surgery."
"Anticoagulation, steroids, plasma exchange, cyclophosphomide and intravenous immunoglobulin therapy are often used 1. The longterm mortality of catastrophic antiphospholipid syndrome is nearly 50%. Patients may develop further events of catastrophic antiphospholipid syndrome after the initial one."