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Lint: clear-cell-tumour-of-the-lung

Headings Spacing
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"Epidemiology "

Line 2:1 · Never put spaces at either end of headings.

"Clinical presentation "

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"Pathology "

Line 8:1 · Never put spaces at either end of headings.

"Radiographic features "

Line 10:1 · Never put spaces at either end of headings.
Acronyms
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"CCTL usually presents as an incidental peripheral pulmonary nodule. On histology it shows evidence of perivascular or melanocytic differentiation, being negative for cytokeratin and epithelial membrane antigen, but positive for HMB-45 and sometimes S-100. This immunoprofile distinguishes CCTL from both metastatic renal cell carcinoma and primary clear cell carcinomas of the lung, which are cytokeratin-positive and lack HMB-45 reactivity."

Line 5:232 · 'HMB' has no definition. Spell it out if it's unfamiliar to the audience.

"CCTL usually presents as an incidental peripheral pulmonary nodule. On histology it shows evidence of perivascular or melanocytic differentiation, being negative for cytokeratin and epithelial membrane antigen, but positive for HMB-45 and sometimes S-100. This immunoprofile distinguishes CCTL from both metastatic renal cell carcinoma and primary clear cell carcinomas of the lung, which are cytokeratin-positive and lack HMB-45 reactivity."

Line 5:427 · 'HMB' has no definition. Spell it out if it's unfamiliar to the audience.

"CCTLs are composed of large polygonal cells with clear cytoplasm because the abundant glycogen dissolves during standard processing. Glycogen is a metabolic product of perivascular epitheliod cells. Periodic acid-Schiff (PAS) staining highlights glycogen and is typically positive. CCTLs are immunoreactive for HMB-45 and vimentin, but negative for cytokeratin and epithelial markers, supporting perivascular or melanocytic differentiation. The absence of cytokeratin and epithelial membrane antigen helps distinguish CCTL from metastatic renal cell carcinoma and other clear cell neoplasms 7."

Line 9:315 · 'HMB' has no definition. Spell it out if it's unfamiliar to the audience.
Illusions
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"It was initially described by A A Liebow and B Castleman in 1963 2."

Line 16:42 · 'A' is repeated!
Headings Valid
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Expected headings

  • H1 Terminology
  • H1 Usage
  • H1 Epidemiology
  • H2 Risk factors
  • H2 Associations
  • H1 Clinical presentation
  • H2 Complications
  • H1 Diagnosis
  • H2 Diagnostic criteria
  • H2 Diagnostic clues
  • H1 Pathology
  • H2 Aetiology
  • H2 Location
  • H2 Classification
  • H2 Macroscopic appearance
  • H2 Microscopic appearance
  • H2 Immunophenotype
  • H2 Markers
  • H2 Genetics
  • H1 Radiographic features
  • H2 Plain radiograph
  • H2 Mammography
  • H2 Antenatal ultrasound
  • H2 Transoesophageal echocardiography
  • H2 Ultrasound
  • H2 CT
  • H3 Dual-energy CT
  • H2 Angiography (DSA)
  • H2 MRI
  • H2 CT/MRI
  • H2 Nuclear medicine
  • H3 PET-CT
  • H3 PET-MRI
  • H1 Radiology report
  • H1 Treatment and prognosis
  • H2 Complications
  • H1 History and etymology
  • H1 Differential diagnosis
  • H2 Clinical differential diagnosis
  • H1 Practical points
  • H1 See also

"Epidemiology "

Line 2:1 · "Epidemiology " is not a recognised heading for this article type.

"Clinical presentation "

Line 6:1 · "Clinical presentation " is not a recognised heading for this article type.

"Pathology "

Line 8:1 · "Pathology " is not a recognised heading for this article type.

"Radiographic features "

Line 10:1 · "Radiographic features " is not a recognised heading for this article type.

"CT"

Line 12:1 · "CT" should be H2, not H3.
There Is
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"There are few reported cases, affecting males and females in their third to seventh decades 7."

Line 3:4 · Don't start a sentence with 'There are'.
Oxford Comma
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"Nodules are solitary, smooth and round, well-defined and homogeneous, located in the lung periphery."

Line 11:16 · Use the Oxford comma in 'solitary, smooth and round'.
Biographical Lifespan
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"History and etymology"

Line 15:1 · A bold element in the History and etymology section should be a person; it would be useful to have their lifespan details: '<h4>History and etymology</h4> <p>It was initially described by <strong>A A Liebow</strong> '
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