"Cutaneous angiosarcomas are rare and account for less than 1% of all sarcomas. They most commonly affect older adults, particularly those aged 60-80 years, with a slight male predominance 2,3. Certain subtypes, such as post-radiation angiosarcoma, can develop in younger individuals 4."
"chronic lymphoedema: Stewart-Treves syndrome refers to angiosarcoma arising in chronic lymphoedematous limbs, typically post-mastectomy."
"chronic lymphoedema: Stewart-Treves syndrome refers to angiosarcoma arising in chronic lymphoedematous limbs, typically post-mastectomy."
"radiation exposure: Secondary angiosarcomas have been reported after radiotherapy for breast cancer or other malignancies."
"environmental exposure: Chemicals such as vinyl chloride and arsenic have been implicated but are less common in modern cases."
"radiotherapy: often used as an adjunct to surgery, particularly in high-risk cases."
"T2: high signal intensity"
"T1 C+ (Gd): heterogeneous enhancement"
"radiation exposure: Secondary angiosarcomas have been reported after radiotherapy for breast cancer or other malignancies."
"environmental exposure: Chemicals such as vinyl chloride and arsenic have been implicated but are less common in modern cases."
"Tumour cells may express endothelial markers such as CD31, CD34, and ERG 6."
Expected headings
"Immunohistochemistry"
"Signal characteristics"
"systemic therapy: limited efficacy; paclitaxel or doxorubicin-based chemotherapy may be used for advanced disease"