"Ultrasound "
"Differential diagnosis "
"T1: low signal 1"
"fat saturation sequences: high signal 1"
"T1 C+ (Gd): enhances 1"
"solitary, mostly well-defined iso- or hypo-dense mass in the subcutaneous tissues 3"
"T2: high signal; usually higher than or equal to adjacent subcutaneous fat 1"
"Fibrosarcomatous transformation of dermatofibrosarcoma protuberans (FS-DFSP / fibrosarcoma ex-DFSP) is an uncommon and aggressive variant of DFSP, associated with a higher tendency for local recurrence and distant metastasis 8,9. Wide excision with ≥2 cm margins or Micrographic Mohs surgery with smaller margins is the treatment of choice for FS-DFSP, to avoid local recurrence and metastasis. Radiation has a role in cases with incomplete surgical resection, whereas the PDGFR-inhibitor imatinib is effective in irresectable, locally advanced and metastatic cases 8."
"Fibrosarcomatous transformation of dermatofibrosarcoma protuberans (FS-DFSP / fibrosarcoma ex-DFSP) is an uncommon and aggressive variant of DFSP, associated with a higher tendency for local recurrence and distant metastasis 8,9. Wide excision with ≥2 cm margins or Micrographic Mohs surgery with smaller margins is the treatment of choice for FS-DFSP, to avoid local recurrence and metastasis. Radiation has a role in cases with incomplete surgical resection, whereas the PDGFR-inhibitor imatinib is effective in irresectable, locally advanced and metastatic cases 8."
Expected headings
"Ultrasound "
"CT"
"MRI"
"Differential diagnosis "
"ill-defined margins, irregular or lobulated shape with infiltration into peripheral fat"
"In contrast, dermatofibroma is typically well-circumscribed, superficial and with low cellularity, less subcutaneous infiltration and more homogeneous. Dermatofibromas lack the deep, infiltrative and tentacle-like features seen in DFSP and do not show aggressive-type enhancement or perfusion patterns on MRI or ultrasound."
"In contrast, dermatofibroma is typically well-circumscribed, superficial and with low cellularity, less subcutaneous infiltration and more homogeneous. Dermatofibromas lack the deep, infiltrative and tentacle-like features seen in DFSP and do not show aggressive-type enhancement or perfusion patterns on MRI or ultrasound."
"T2: high signal; usually higher than or equal to adjacent subcutaneous fat 1"
"History and etymology"