"Fibrillary astrocytomas are predominantly composed of a tumour matrix rich with neuroglial fibrils, which give the tumour its name and firm consistency 4. Within the tumour matrix are embedded neoplastic fibrillary astrocytes with mild nuclear atypia (enlarged, irregular contour, hyperchromasia and coarsened nuclear chromatin pattern) and a low cellular density 2-3. The nuclei are elongated and appear "naked" 4."
"Often microcystic spaces containing mucinous fluid are present 2,5. Like all tumours derived from astrocytes, fibrillary astrocytomas stain with glial fibrillary acidic protein (gFAP) 2-3."
"Fibrillary astrocytomas are predominantly composed of a tumour matrix rich with neuroglial fibrils, which give the tumour its name and firm consistency 4. Within the tumour matrix are embedded neoplastic fibrillary astrocytes with mild nuclear atypia (enlarged, irregular contour, hyperchromasia and coarsened nuclear chromatin pattern) and a low cellular density 2-3. The nuclei are elongated and appear "naked" 4."