"Gastrointestinal leiomyomas are rare in the gastrointestinal tract except in the oesophagus, where they are the most common benign mesenchymal tumour (up to 70–80% of oesophageal mesenchymal tumours) 2-4."
"They are much rarer than GIST and do not express CD117 (c-KIT). These tumours need to be differentiated from GIST, as the management and prognosis show variations 13."
"They are much rarer than GIST and do not express CD117 (c-KIT). These tumours need to be differentiated from GIST, as the management and prognosis show variations 13."
"They are much rarer than GIST and do not express CD117 (c-KIT). These tumours need to be differentiated from GIST, as the management and prognosis show variations 13."
"Immunohistochemistry shows positive smooth muscle actin (SMA) and desmin with negative CD117 (c-KIT), DOG1 and CD34 markers."
"These tumours generally show no malignant potential and do not harbour KIT or PDGFRA mutations 8."
"no necrosis or ulceration (unlike GIST)"
"show a lower arterial phase enhancement than GIST"
"GIST 12"
"small & large intestines: may arise submucosally or intramurally"
"Clinical Presentation"
"Treatment & Prognosis"
"Differential Diagnosis"
"Endoscopic ultrasound generally shows a well-defined homogenous submucosal mass 6,15."
Expected headings
"Clinical Presentation"
"Endoscopic ultrasound"
"Treatment & Prognosis"
"Differential Diagnosis"
"oesophagus: most common site; often found incidentally 4"