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Citation Preceding Space

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"GSSD is caused by autosomal dominant point mutations in the prion protein gene, for example missense or nonsense mutations ¹⁰. This results in a misfolded pathogenic isoform of the prion protein gene (PrPSc), which aggregate to form amyloid deposits that damage brain parenchyma¹⁰."

Line 9:293 · Citations must have a preceding space, e.g. needs evidence 2. '10'

Emphasis

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"Gerstmann-Straussler-Scheinker disease (GSSD) is a rare type of transmissible spongiform encephalopathy. It manifests with dementia and/or ataxia and is due to a mutation in the prion protein (PRNP) gene, which is inherited in an autosomal dominant pattern."

Line 1:221 · Italics should be used only in exceptional circumstances: 'PRNP'

Headings Case

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"Treatment and Prognosis"

Line 15:5 · 'Treatment and Prognosis' should use sentence-style capitalization.

Headings Valid

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Expected headings

H1 Terminology
H1 Usage
H1 Epidemiology
H2 Risk factors
H2 Associations
H1 Clinical presentation
H2 Complications
H1 Diagnosis
H2 Diagnostic criteria
H2 Diagnostic clues
H1 Pathology
H2 Aetiology
H2 Location
H2 Classification
H2 Macroscopic appearance
H2 Microscopic appearance
H2 Immunophenotype
H2 Markers
H2 Genetics
H1 Radiographic features
H2 Plain radiograph
H2 Mammography
H2 Antenatal ultrasound
H2 Transoesophageal echocardiography
H2 Ultrasound
H2 CT
H3 Dual-energy CT
H2 Angiography (DSA)
H2 MRI
H2 CT/MRI
H2 Nuclear medicine
H3 PET-CT
H3 PET-MRI
H1 Radiology report
H1 Treatment and prognosis
H2 Complications
H1 History and etymology
H1 Differential diagnosis
H2 Clinical differential diagnosis
H1 Practical points
H1 See also

"Treatment and Prognosis"

Line 15:1 · "Treatment and Prognosis" is not a recognised heading for this article type.

Links

prion-diseases

creutzfeldt-jakob-disease

gerstmann-syndrome

Lint: gerstmann-straussler-scheinker-disease