"Glioblastoma also are reported to have higher rCBV values compared to metastases13."
"Cho/Cr ratio > 1.24: sensitivity 100%, specificity 88.9%, positive (PPV) 80.0%, and negative predictive values (NPV) 100% 7"
"Cho/NAA ratio > 1.11: sensitivity 100%, specificity 91.1%, PPV 83.3%, and NPV 100% 7"
"MR perfusion"
"MR spectroscopy"
"elevated in peri-enhancing high T2 signal parenchyma in gliomas representing presence of abnormal blood vessels 2"
"Arterial spin labelled (ASL) perfusion has also shown increased cerebral blood flow (CBF) in the peri-enhancing high T2 signal brain of gliomas 3."
"* the term "peri-tumoural" is unfortunate as it is now well known that in gliomas tumour cells extend well beyond the enhancing margins, and as such what is being referred to is non-enhancing tumour or "peri-enhancement""
"* the term "peri-tumoural" is unfortunate as it is now well known that in gliomas tumour cells extend well beyond the enhancing margins, and as such what is being referred to is non-enhancing tumour or "peri-enhancement""
"higher in enhancing component of tumours, representing more intact BBB in gliomas 2"
"non-enhancing "peritumoural" component *: elevation of Cho/Cr and Cho/NAA suggests glioma and reflects tumour infiltration 6,7"
"Cho/Cr ratio > 1.24: sensitivity 100%, specificity 88.9%, positive (PPV) 80.0%, and negative predictive values (NPV) 100% 7"
"Cho/NAA ratio > 1.11: sensitivity 100%, specificity 91.1%, PPV 83.3%, and NPV 100% 7"
"Cho/NAA ratio > 1.11: sensitivity 100%, specificity 91.1%, PPV 83.3%, and NPV 100% 7"
"NAA peak"
"although the NAA peak is suppressed in both glioma and metastasis relative to normal brain, a metastasis has no neuronal tissue and therefore should have no NAA, provided the voxel is entirely intralesional so as not to unintentionally include normal adjacent brain"
"although the NAA peak is suppressed in both glioma and metastasis relative to normal brain, a metastasis has no neuronal tissue and therefore should have no NAA, provided the voxel is entirely intralesional so as not to unintentionally include normal adjacent brain"
"Cho/NAA ratio > 1.11: sensitivity 100%, specificity 91.1%, PPV 83.3%, and NPV 100% 7"
Expected headings
"Systemic malignancy"
"Non-enhancing tumour"
"Multiplicity"
"Location"
"Morphology"
"MR perfusion"
"MR spectroscopy"
"Conversely, occasionally a patient who has a history of malignancy will have a concurrent unrelated glioblastoma; they are, after all, fairly common tumours in the elderly."