"T1: low to intermediate signal"
"T1 C+ (Gd): shows avid contrast enhancement (usually uniform) due to high vascularity"
"T2: intense high signal"
"Glomus tumours are positive for SMA, MSA, calponin, h-caldesmon, and collagen type IV. They are negative for cytokeratin and S100. MIR143-NOTCH gene fusions are present in more than half of glomus tumours 8."
"Glomus tumours are positive for SMA, MSA, calponin, h-caldesmon, and collagen type IV. They are negative for cytokeratin and S100. MIR143-NOTCH gene fusions are present in more than half of glomus tumours 8."
"They classically present in the young to middle-aged (40 to 50 years of age) population 7. There is a recognised female predilection. They can be multiple in ~10% of cases. Glomus tumours account for 1-5% of the soft-tissue tumours in the hand 4."
"Glomus tumours originate from the neuromyoarterial plexus (modified smooth muscle cells of the glomus body). They are best thought of as hamartomas rather than true tumours. There are two main components on microscopy:"
"The lesion usually presents as a small firm red-blue nodule under the fingernail and is exquisitely painful and sensitive to cold temperature and touch. Sometimes the pain is worse at night; it may disappear when a tourniquet is applied."
"Approximately 75% occur in the hand 4; a subungual position is characteristic."