"They are often classified as benign or malignant using the Fanburg-Smith criteria (especially for soft tissue lesions) 3,4,5. These histologic criteria include spindled cells, increased mitoses, necrosis, high nuclear to cytoplasmic ratio, nuclear pleomorphism, and prominent nucleoli. Lesions with 3 or more of these features are designated as malignant, 1 or 2 as atypical, and 0 as benign."
"They are often classified as benign or malignant using the Fanburg-Smith criteria (especially for soft tissue lesions) 3,4,5. These histologic criteria include spindled cells, increased mitoses, necrosis, high nuclear to cytoplasmic ratio, nuclear pleomorphism, and prominent nucleoli. Lesions with 3 or more of these features are designated as malignant, 1 or 2 as atypical, and 0 as benign."