"Haemolytic-uraemic syndrome affects ~ 2:100,000 people worldwide 3. It is most commonly seen in young children."
"The term was coined by Swiss physician Conrad von Gasser (1912–1982) in 1955. E. coli as an aetiological factor was proposed by Mohamed A. Karmali in 1985 2,4."
"Shiga toxin is named after Japanese physician and bacteriologist Kyoshi Shiga (1871–1957), as is the genus Shigella."
"Shiga toxin is named after Japanese physician and bacteriologist Kyoshi Shiga (1871–1957), as is the genus Shigella."
"In over 90% of cases, haemolytic-uraemic syndrome occurs following a gastrointestinal infection with Shiga toxin-producing E. coli (STEC). Some cases are associated with medical conditions such as collagen vascular diseases, such as systemic lupus erythematosus, underlying malignancy, or medications such as ciclosporin, oral contraceptives, or 5-fluoro-uracyl."
"Shiga toxin is named after Japanese physician and bacteriologist Kyoshi Shiga (1871–1957), as is the genus Shigella."
"There are two forms of this syndrome:"
"Injury to the endothelium of the capillaries results in mechanical destruction of the erythrocytes. The kidneys can be the only organ involved; however, involvement of other organs, such as liver, pancreas, heart, intestine, and muscles, is also possible."
"Injury to the endothelium of the capillaries results in mechanical destruction of the erythrocytes. The kidneys can be the only organ involved; however, involvement of other organs, such as liver, pancreas, heart, intestine, and muscles, is also possible."