"Haemophilia is an X-linked recessive disease affecting mainly males. Haemarthroses may be spontaneous or result from minor trauma and typically first occurs before the age of two and continues to occur into adolescence. It is usual for the same joint to be repeatedly involved. In adulthood, haemarthroses are uncommon. However, proliferative chronically inflamed synovium results in the development of haemophilic arthropathy.Repeated haemarthroses result in the intra-articular deposition of iron, which leads to the proliferation of the synovium, neoangiogenesis, and ultimately damage to both the articular cartilage and subchondral bone 8."
"rhenium186 is emerging as the preferred isotope over phosphorus32 and yttrium90 particularly in medium-sized joints 5"
"rhenium186 is emerging as the preferred isotope over phosphorus32 and yttrium90 particularly in medium-sized joints 5"
"rhenium186 is emerging as the preferred isotope over phosphorus32 and yttrium90 particularly in medium-sized joints 5"
"Pettersson score: elbows, knees, and ankles radiographs; recommended by World Federation of Haemophilia 9"
Expected headings
"Classification"
"There are several imaging-based classification systems 9:"
"Pettersson score: elbows, knees, and ankles radiographs; recommended by World Federation of Haemophilia 9"
"secondary degenerative disease: symmetrical loss of joint cartilage involving all compartments equally with periarticular erosions and subchondral cysts, osteophytes and sclerosis"
"chronic haemarthroses and hyperaemia leading to growth deformities (e.g. epiphyseal enlargement, widened intercondylar notch of the knee)"