"The disease is characterised by the presence of Reed-Sternberg cells (considered to be a type of B cell). These cells however only occupy a very small proportion ("
"Positive for CD15/CD30 and negative for CD20/CD45/EMA:"
"Positive for CD 19, 20, 22, 79a/EMA and negative for CD15/CD30:"
"Prognosis depends on stage as well as several other factors such as age, serological markers (ESR), presence of B symptoms, and histological tumour subtype:"
Expected headings
"Subtypes"
"Classical"
"Non-classical"
"Nodal disease"
"Extranodal disease"
"Staging"
"There is a bimodal distribution in the age of affected patients, with peaks in young adults (15-34 years) and older patients (>55 years)."
"There are five recognised histological subtypes, subdivided into two groups, classical and non-classical."
"There are five recognised histological subtypes, subdivided into two groups, classical and non-classical."