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Lint: immunohistochemistry

Acronyms
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"Both processes employ antibodies to specific antigens (e.g. cellular proteins like GFAP or EMA). There are now a significant number of antibodies, and typically multiple antibodies (a panel) will be used based on the differential diagnosis suggested by the patient's history and standard H&E examination of the sample."

Line 7:90 · 'GFAP' has no definition. Spell it out if it's unfamiliar to the audience.

"Both processes employ antibodies to specific antigens (e.g. cellular proteins like GFAP or EMA). There are now a significant number of antibodies, and typically multiple antibodies (a panel) will be used based on the differential diagnosis suggested by the patient's history and standard H&E examination of the sample."

Line 7:105 · 'EMA' has no definition. Spell it out if it's unfamiliar to the audience.
Headings Valid
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Expected headings

  • H1 Terminology
  • H1 Usage
  • H1 Epidemiology
  • H2 Risk factors
  • H2 Associations
  • H1 Clinical presentation
  • H2 Complications
  • H1 Diagnosis
  • H2 Diagnostic criteria
  • H2 Diagnostic clues
  • H1 Pathology
  • H2 Aetiology
  • H2 Location
  • H2 Classification
  • H2 Macroscopic appearance
  • H2 Microscopic appearance
  • H2 Immunophenotype
  • H2 Markers
  • H2 Genetics
  • H1 Radiographic features
  • H2 Plain radiograph
  • H2 Mammography
  • H2 Antenatal ultrasound
  • H2 Transoesophageal echocardiography
  • H2 Ultrasound
  • H2 CT
  • H3 Dual-energy CT
  • H2 Angiography (DSA)
  • H2 MRI
  • H2 CT/MRI
  • H2 Nuclear medicine
  • H3 PET-CT
  • H3 PET-MRI
  • H1 Radiology report
  • H1 Treatment and prognosis
  • H2 Complications
  • H1 History and etymology
  • H1 Differential diagnosis
  • H2 Clinical differential diagnosis
  • H1 Practical points
  • H1 See also

"Direct vs indirect"

Line 8:1 · "Direct vs indirect" is not a recognised heading for this article type.

"Slide preparation"

Line 13:1 · "Slide preparation" is not a recognised heading for this article type.

"Antigen retrieval"

Line 22:1 · "Antigen retrieval" is not a recognised heading for this article type.

"Primary antibody"

Line 24:1 · "Primary antibody" is not a recognised heading for this article type.

"Secondary antibody"

Line 26:1 · "Secondary antibody" is not a recognised heading for this article type.

"Chromogen application"

Line 28:1 · "Chromogen application" is not a recognised heading for this article type.

"Counterstaining"

Line 30:1 · "Counterstaining" is not a recognised heading for this article type.

"Internal control"

Line 32:1 · "Internal control" is not a recognised heading for this article type.
There Is
suggestion

"There are many variations on exactly how immunohistochemistry is performed and it is outside the scope of this article to cover any in great detail. Still, broadly speaking they can be divided into:"

Line 2:4 · Don't start a sentence with 'There are'.

"Both processes employ antibodies to specific antigens (e.g. cellular proteins like GFAP or EMA). There are now a significant number of antibodies, and typically multiple antibodies (a panel) will be used based on the differential diagnosis suggested by the patient's history and standard H&E examination of the sample."

Line 7:115 · Don't start a sentence with 'There are'.
Semicolons
suggestion

"immunofluorescence, where the antibody is tagged with a compound that fluoresces; and"

Line 4:88 · Use semicolons judiciously.