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Lint: incontinentia-pigmenti

En Dash
error

"Incontinentia pigmenti is rare and the true prevalence is unknown. Approximately 1000 cases have been reported in the literature 4. There is a female:male sex ratio of 2037:1 6."

Line 3:185 · Use a hyphen-minus ('-') instead of an en-dash ('–').

"The syndrome was described in 1928 by Marion Sulzberger (18951983), an American dermatologist."

Line 72:82 · Use a hyphen-minus ('-') instead of an en-dash ('–').
List Punctuation
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"vesicles and linear inflammatory blistering occurring at birth or during the first two months of life."

Line 7:105 · Do not put full stops at the end of a list item.

"hyperkeratotic, verrucous, linear plaques that may last months."

Line 8:64 · Do not put full stops at the end of a list item.

"brown or greyish-blue hyperpigmentation, distributed in Blaschko's lines (lines of normal cell development in the skin) or in swirling patterns that appear in infancy and fade slowly until they disappear in adulthood."

Line 9:215 · Do not put full stops at the end of a list item.

"hypopigmented linear macules on the trunk and limbs usually observed in adulthood."

Line 10:80 · Do not put full stops at the end of a list item.
Adjectival Hyphens
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"When it occurs in males it is usually lethal; however, cases have been reported in male patients with Klinefelter syndrome or with a mosaic karyotype for this syndrome (post-zygotic mutations) 1-2."

Line 37:180 · Only use medical adjectival hyphens where the letters at the end and start of the compound word are the same, e.g. post-transplant. In this case, don't use the hyphen: 'post-zygotic'.
Citation Syntax
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"When it occurs in males it is usually lethal; however, cases have been reported in male patients with Klinefelter syndrome or with a mosaic karyotype for this syndrome (post-zygotic mutations) 1-2."

Line 37:204 · Citations are separated by commas, except when the range is over 2.
Acronyms
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"This condition is related to mutations in NF-kappa B essential modulator (NEMO) gene of the kappa B genetic factor, located in the long arm of the Xq28 chromosome 6. This gene codifies proteins that help protect cells from apoptosis in response to certain signals."

Line 36:46 · 'NF' has no definition. Spell it out if it's unfamiliar to the audience.

"This condition is related to mutations in NF-kappa B essential modulator (NEMO) gene of the kappa B genetic factor, located in the long arm of the Xq28 chromosome 6. This gene codifies proteins that help protect cells from apoptosis in response to certain signals."

Line 36:78 · 'NEMO' has no definition. Spell it out if it's unfamiliar to the audience.
Personal Names
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"The syndrome was first described by Garrod A.E. et al. in 1906."

Line 70:1 · Titles and initials take no full stops: 'A.E. '.
Headings Valid
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Expected headings

  • H1 Terminology
  • H1 Usage
  • H1 Epidemiology
  • H2 Risk factors
  • H2 Associations
  • H1 Clinical presentation
  • H2 Complications
  • H1 Diagnosis
  • H2 Diagnostic criteria
  • H2 Diagnostic clues
  • H1 Pathology
  • H2 Aetiology
  • H2 Location
  • H2 Classification
  • H2 Macroscopic appearance
  • H2 Microscopic appearance
  • H2 Immunophenotype
  • H2 Markers
  • H2 Genetics
  • H1 Radiographic features
  • H2 Plain radiograph
  • H2 Mammography
  • H2 Antenatal ultrasound
  • H2 Transoesophageal echocardiography
  • H2 Ultrasound
  • H2 CT
  • H3 Dual-energy CT
  • H2 Angiography (DSA)
  • H2 MRI
  • H2 CT/MRI
  • H2 Nuclear medicine
  • H3 PET-CT
  • H3 PET-MRI
  • H1 Radiology report
  • H1 Treatment and prognosis
  • H2 Complications
  • H1 History and etymology
  • H1 Differential diagnosis
  • H2 Clinical differential diagnosis
  • H1 Practical points
  • H1 See also

"CNS"

Line 39:1 · "CNS" is not a recognised heading for this article type.

"Head and face"

Line 50:1 · "Head and face" is not a recognised heading for this article type.

"Musculoskeletal"

Line 59:1 · "Musculoskeletal" is not a recognised heading for this article type.
There Is
suggestion

"Incontinentia pigmenti is rare and the true prevalence is unknown. Approximately 1000 cases have been reported in the literature 4. There is a female:male sex ratio of 20–37:1 6."

Line 3:147 · Don't start a sentence with 'There is'.

"There are four classic cutaneous phases that may be concomitant or sequential 1:"

Line 5:4 · Don't start a sentence with 'There are'.

"There is no specific treatment. The skin lesions generally regress spontaneously and all the treatment is based on symptomatology."

Line 68:4 · Don't start a sentence with 'There is'.
Semicolons
suggestion

"When it occurs in males it is usually lethal; however, cases have been reported in male patients with Klinefelter syndrome or with a mosaic karyotype for this syndrome (post-zygotic mutations) 1-2."

Line 37:48 · Use semicolons judiciously.
Biographical Lifespan
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"History and etymology"

Line 69:1 · A bold element in the History and etymology section should be a person; it would be useful to have their lifespan details: '<h4>History and etymology</h4> <p>The syndrome was first described by <strong>Garrod A.E.</strong> '