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Lint: kernicterus

Headings Spacing
error

"MRI "

Line 31:1 · Never put spaces at either end of headings.
Acronyms
warning

"haemolysis (e.g. glucose-6-phosphate dehydrogenase (G6PD) deficiency, ABO or Rh incompatibility)"

Line 22:85 · 'ABO' has no definition. Spell it out if it's unfamiliar to the audience.
Strong
warning

"MR spectroscopy has been infrequently reported in the literature on kernicterus; existing studies have reported increased levels of glutamine and glutamate, along with decreased levels of choline and N-acetylaspartate 9."

Line 38:4 · Generally, don't use bold in text: '<strong>MR spectroscopy</strong>'
Headings Valid
warning

Expected headings

  • H1 Terminology
  • H1 Usage
  • H1 Epidemiology
  • H2 Risk factors
  • H2 Associations
  • H1 Clinical presentation
  • H2 Complications
  • H1 Diagnosis
  • H2 Diagnostic criteria
  • H2 Diagnostic clues
  • H1 Pathology
  • H2 Aetiology
  • H2 Location
  • H2 Classification
  • H2 Macroscopic appearance
  • H2 Microscopic appearance
  • H2 Immunophenotype
  • H2 Markers
  • H2 Genetics
  • H1 Radiographic features
  • H2 Plain radiograph
  • H2 Mammography
  • H2 Antenatal ultrasound
  • H2 Transoesophageal echocardiography
  • H2 Ultrasound
  • H2 CT
  • H3 Dual-energy CT
  • H2 Angiography (DSA)
  • H2 MRI
  • H2 CT/MRI
  • H2 Nuclear medicine
  • H3 PET-CT
  • H3 PET-MRI
  • H1 Radiology report
  • H1 Treatment and prognosis
  • H2 Complications
  • H1 History and etymology
  • H1 Differential diagnosis
  • H2 Clinical differential diagnosis
  • H1 Practical points
  • H1 See also

"MRI "

Line 31:1 · "MRI " is not a recognised heading for this article type.
Commas
suggestion

"Nearly all affected infants will have clinical features of acute bilirubin encephalopathy, such as jaundice, somnolence, hypertonia, opisthotonos, and retrocollis, before manifestation of these permanent neurological signs 1. These early signs are often unfortunately mistaken for mimics such as sepsis or hypoglycaemia 1."

Line 13:100 · More than 5 commas in a single sentence might make it more difficult to read.

"As a result, this unconjugated bilirubin deposits symmetrically in the brain, with a predilection for the globi pallidi, subthalamic nuclei, hippocampus (especially CA2-CA3), putamen, thalamus, and cranial nerve nuclei (especially of CN III, IV, and VI) 1,2,5-10. Macroscopically, these areas have a characteristic yellow appearance 1,2,5-10."

Line 17:15 · More than 5 commas in a single sentence might make it more difficult to read.
There Is
suggestion

"There are numerous underlying causes for unconjugated hyperbilirubinaemia, and thus kernicterus, in infancy 1-3,5-10:"

Line 20:4 · Don't start a sentence with 'There are'.

"There is no disease-modifying treatment available, and the prognosis is poor 1,2,6. Early management of neonatal hyperbilirubinaemia, with therapies such as phototherapy and exchange transfusions, should be employed to prevent kernicterus 1,2,6."

Line 40:4 · Don't start a sentence with 'There is'.
Inline EG
suggestion

"haemolysis (e.g. glucose-6-phosphate dehydrogenase (G6PD) deficiency, ABO or Rh incompatibility)"

Line 22:26 · Consider replacing a bracketed e.g. with an inline e.g. after a comma.

"disorders of hepatic bilirubin metabolism (e.g. Crigler-Najjar syndrome)"

Line 24:50 · Consider replacing a bracketed e.g. with an inline e.g. after a comma.

"acquired defects in bilirubin conjugation (e.g. Lucey-Driscoll syndrome)"

Line 25:50 · Consider replacing a bracketed e.g. with an inline e.g. after a comma.
Semicolons
suggestion

"MR spectroscopy has been infrequently reported in the literature on kernicterus; existing studies have reported increased levels of glutamine and glutamate, along with decreased levels of choline and N-acetylaspartate 9."

Line 38:100 · Use semicolons judiciously.