"Macromolecular complexes include both macrohormones and macroenzymes, which consist of hormones and enzymes respectively covalently bound to carrier molecules, e.g. immunoglobulins, or occasionally the molecule may self-polymerise. Their primary importance lies in their ability to produce an artifactually-high level of the particular hormone/enzyme in the blood as standard laboratory assays do not distinguish between the unbound and bound forms of the hormone/enzyme, e.g. in hyperamylasaemia the serum amylase appears to be elevated but may actually be normal. This may lead to inappropriate investigations and therapy."
"macro-gamma-glutamyl transferase (macro-GGT)"
Expected headings
"Macrohormones"
"Macroenzymes"
"Immunoglobulin-bound"
"Non-immunoglobulin-bound"