"In the revised 4th edition (2016) of the WHO classification, the term medulloepithelioma was preserved as some tumours with this histological appearance did not have C19MC-amplification 3."
"The medulloepithelioma pattern of embryonal tumours with multilayered rosettes mimics the appearance of the primitive neural tube with cells arranged in tubular, papillary, or trabecular patterns, often with differentiation into multiple cell types (e.g. glial, neuronal or mesenchymal) 1. Mitotic figures are common with a high Ki-67 proliferation index (20-80%) 6."