"Mucoepidermoid carcinoma (MEC) is the most common of the salivary gland–type tumours of the lung (SGTTLs) 9. The tumour is thought to account for ~ 0.1-0.2% of primary lung cancers 4. MEC may be encountered in any age group, however, most cases have been seen in adults 4. There appears to be slight male preponderance with a male-to-female distribution of almost 1.5:1 9."
"Mucoepidermoid carcinoma (MEC) is the most common of the salivary gland–type tumours of the lung (SGTTLs) 9. The tumour is thought to account for ~ 0.1-0.2% of primary lung cancers 4. MEC may be encountered in any age group, however, most cases have been seen in adults 4. There appears to be slight male preponderance with a male-to-female distribution of almost 1.5:1 9."
"May aid in differentiation of mucoepidermoid carcinoma from other lung tumours 5, but first of all, it has been shown to have high accuracy in detection of histopathological tumour differentiation 10-11:"
"Hence prediction of prognosis (and need for more aggressive treatment) may be possible 10-11."
"other usable features include absence of an in situ carcinomatous component and the presence of low-grade mucoepidermoid areas in some of these high-grade lesions"
"Symptoms are dependent on the size and location of the neoplasms. Large central tumours can cause symptoms of obstruction, with pneumonia, dyspnoea or chest pain, whilst more peripheral lesions may be asymptomatic. In these cases, they are frequently encountered on routine chest X-ray."
Expected headings
"Gross pathology"
"Histopathology"
"Differentials on biopsy"
"FDG PET-CT"
"Mucoepidermoid carcinoma of lung may be solid, cystic or both, may show overtly mucoid features. Components comprise clear cells, squamoid cells or transitional polygonal cells, interspersed with areas containing mucus-secreting glandular cells."
"Symptoms are dependent on the size and location of the neoplasms. Large central tumours can cause symptoms of obstruction, with pneumonia, dyspnoea or chest pain, whilst more peripheral lesions may be asymptomatic. In these cases, they are frequently encountered on routine chest X-ray."
"low-grade tumours characteristically demonstrate bland cytologic features; mitotic activity is minimal or absent"
"high-grade mucoepidermoid carcinoma demonstrates a greater degree of cytologic anaplasia in both its squamoid and glandular elements; areas of necrosis and haemorrhage may also be present"