"In the same year, Jean-Athanase Sicard (1872–1929, French physician) who had been experimenting with injection of an iodized oil called Lipiodol into the epidural space for the treatment of chronic pain, accidentally injected it into the intrathecal space. It was known that Lipiodol was markedly radiopaque and the patient was fine. And thus, positive contrast myelography was born 8,9."
"The concept of using a contrast agent to better image the contents of the spinal canal was first proposed in 1919 by Walter Dandy (1886-1946, American neurosurgeon) who had pioneered pneumoencephalography, wherein air was instilled into the subarachnoid space as a negative contrast agent for evaluating structures of the brain 5. This was first carried out in 1921 6,7. Although crude, requiring extraction of an equivalent volume of cerebrospinal fluid to instilled air, and extremely painful, air-contrast myelography (a.k.a. pneumomyelography) techniques allowed some visualisation of the intraspinal soft tissues as imaged by fluoroscopy 12."
"In the same year, Jean-Athanase Sicard (1872–1929, French physician) who had been experimenting with injection of an iodized oil called Lipiodol into the epidural space for the treatment of chronic pain, accidentally injected it into the intrathecal space. It was known that Lipiodol was markedly radiopaque and the patient was fine. And thus, positive contrast myelography was born 8,9."
Expected headings
"History"
"Myelography is a generic term to refer to an imaging procedure performed to evaluate the subarachnoid spaces within the spinal canal and is performed after the intrathecal injection of either contrast media (for fluoroscopy, xrays, CT and MRI) or radiopharmaceuticals."