"A tumour with a swirling pattern of the perineal region without the involvement of the viscera in a woman in her 3rd or 4th decade might reflect an aggressive angiomyxoma, if the lesion is intramuscular and well defined an intramuscular myxoma is very likely. If a myxoid lesion is located in the extremities of a patient in the 6th decade of life and shows an ill-defined appearance a myxofibrosarcoma should be considered. If it is located in the distal extremities with subcutaneous involvement one should think of myxoinflammatory fibroblastic sarcoma (MIFS). The presence of fatty components should suggest a myxoid liposarcoma. Are there ossifications present? – think of ossifying fibromyxoid tumours and noncalcified large lobulated tumours in the proximal lower extremities or limb-girdle regions should rise the thought of extraskeletal myxoid chondrosarcoma 2."
"A simplified classification for myxoid soft tissue tumours proposed by Baheti et al. lists the most important benign and malignant neoplasms 2:"
"The differential diagnosis includes many tumour-like myxoid lesions e.g. ganglion cysts and synovial cysts peripheral nerve sheath tumours including neurofibromas and schwannomas 2,3 and other benign and malignant soft tissue tumours 2."
Expected headings
"Benign myxoid soft tissue tumours"
"Malignant myxoid soft tissue tumours"
"Signal characteristics"
"Myxoid chondrosarcomas, ossifying fibromyxoid tumours, low-grade fibromyxoid sarcoma and myxoinflammatory fibroblastic sarcomas are rare variants from the malignant group 2,3 and superficial angiomyxoma, myxolipoma and acral fibromyxoma are rare benign myxoid tumours 2."
"Myxoid liposarcomas and extraskeletal myxoid chondrosarcomas are typically located within the lower extremities hips, buttocks and trunk 2,6."
"Most myxoid soft tissue tumours will be found in the extremities and less often in the trunk 2,3. Intramuscular myxomas will most often occur intramuscularly and in rare occasions intermuscular or subcutaneous; the thigh is the most commonly affected extremity 2,5."