"Diagnosis "
"Neuromelioidosis describes central nervous system involvement by melioidosis, an atypical infection caused by the Gram-negative bacterium Burkholderia pseudomallei 7. It is a rare infection that is endemic to subtropical regions such as northern Australia and Southeast Asia 7."
"Definitive diagnosis involves isolation of B. pseudomallei from serum, CSF or CNS tissue biopsy 6,7."
Expected headings
"Diagnosis "
"Definitive diagnosis involves isolation of B. pseudomallei from serum, CSF or CNS tissue biopsy 6,7."
"Typical imaging findings are rim-enhancing lesions, leptomeningeal or cranial nerve enhancement, diffusion restriction with supratentorial spread along white matter tracts (tunnel sign) and an affinity for brainstem or frontal lobe involvement 2,3,6."
"Neuromelioidosis may present with a wide range of signs and symptoms depending on the pattern of infection. Significant clinical presentations include fever, headache, focal neurological deficits (e.g. cranial nerve palsy, weakness, ataxia), seizure, and meningism 1,3."