"The term C2 neuralgia is often used synonymously with occipital neuralgia, and reasonably so as the greater occipital nerve is the most common cause of occipital neuralgia and is the medial branch of the dorsal ramus of C2 6. This is not truly a synonym, however, as occipital neuralgia can also be caused by C3 fibres travelling in the lesser occipital nerve or third occipital nerve (see below). As such, unless the cause of pain has been definitively localised to C2, the term occipital neuralgia is preferred."
"Treatment can vary from oral therapy (e.g. tricyclic antidepressants or antiseizure medications), injections (e.g. greater occipital nerve injection, with local anaesthetic with or without corticosteroids or botulinum toxin), radiofrequency ablation or insertion of occipital nerve stimulators 1,4."
"Diagnosis can be confirmed by local anaesthetic greater occipital nerve blockade; this can also be therapeutic 1. Unfortunately, the main differential diagnosis, occipital migraine, can have similar symptoms and can be ameliorated with occipital local anaesthetic injections 1."