"Oligodendroglioma is considered the third most common glioma accounting for 2–5% of primary brain tumours and 5–18% of all glial neoplasms 8."
"Oligodendroglioma is considered the third most common glioma accounting for 2–5% of primary brain tumours and 5–18% of all glial neoplasms 8."
"Pathology "
"Post-contrast CT"
"T1: typically hypointense"
"T2: typically hyperintense (except calcified areas)"
"GRE/SWI: calcium can be seen as areas of "blooming""
"T1 C+ (Gd): contrast enhancement is common but it is not a reliable indicator of tumour grade, with only 50% of oligodendrogliomas enhancing to a variable degree, and usually heterogeneously"
"11C-methionine studies can be used to differentiate oligodendrogliomas from anaplastic oligodendrogliomas. FDG uptake of oligodendrogliomas is similar to normal white matter. FDG uptake of anaplastic oligodendrogliomas is similar to normal grey matter."
"TERT promoter mutation"
"MR perfusion (PWI)"
Expected headings
"Pathology "
"Location"
"Macroscopic appearance"
"Microscopic appearance and classification"
"Molecular markers"
"Non-contrast CT"
"Post-contrast CT"
"PET"
"Oligodendrogliomas are usually tumours of middle-aged adults, occurring most commonly in the 4th and 5th decades of life, somewhat older for grade 3 tumours 10,11. There is a slight male predilection (M:F 1.3:1) 10."
"The vast majority of oligodendrogliomas arise in the cerebral hemispheres, with brainstem, cerebellum and spinal cord being distinctly uncommon 9."
"Tumours are of mixed density (hypodense to isodense). High-attenuation areas within the tumour are likely from calcification (70-90% of oligodendrogliomas are calcified) or, less commonly, haemorrhage. Calcification can be located centrally, peripherally or can be ribbon-like 4. The overlying skull may show pressure remodelling."
"DWI can be used to help differentiate oligodendrogliomas (generally lower grade) from astrocytomas (generally higher grade); astrocytomas have higher ADC values probably because of their lower cellularity and greater hyaluronan proportion 5"