"While the pathophysiology is unknown, OMS is felt to be related to autoimmunity. As a result of cerebellar Purkinje cell dysfunction, oculomotor neurones of the caudal fastigial nucleus of the cerebellum become progressively disinhibited. Anti-neuronal and anti-Purkinje cell antibodies have been implicated in OMS, however, they are not universally isolated in patients with OMD presentations 5."
Expected headings
"Diagnostic criteria"