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Lint: oropharyngeal-p16-negative-cancer-staging

Acronyms
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"Oropharyngeal (p16-) cancer staging refers to TNM staging of carcinomas originating in the oropharynx that are not human papillomavirus (HPV)-associated. This system most commonly pertains to squamous cell carcinomas that tested negative for p16, an immunohistochemical proxy for HPV infection, or were not tested. Rarer oropharyngeal tumours, such as neuroendocrine carcinomas, for which p16 assessment is not required, are also included in this staging system, except for mucosal melanoma, which has its own staging system."

Line 1:70 · 'TNM' has no definition. Spell it out if it's unfamiliar to the audience.

"The following article reflects the 9th version published by the Union for International Cancer Control (UICC) in 2025, which is identical to the 8th version published by the American Joint Committee on Cancer (AJCC) in 2017 1,2."

Line 2:119 · 'UICC' has no definition. Spell it out if it's unfamiliar to the audience.

"The following article reflects the 9th version published by the Union for International Cancer Control (UICC) in 2025, which is identical to the 8th version published by the American Joint Committee on Cancer (AJCC) in 2017 1,2."

Line 2:236 · 'AJCC' has no definition. Spell it out if it's unfamiliar to the audience.

"TX: primary tumour cannot be assessed"

Line 6:16 · 'TX' has no definition. Spell it out if it's unfamiliar to the audience.

"*Note: According to the AJCC 8th edition, involvement of the palatoglossus muscle within the oropharynx does not change the T category and this criterion mainly denotes invasion "anteriorly to the extrinsic muscles of the tongue in the floor of the mouth" 2."

Line 42:28 · 'AJCC' has no definition. Spell it out if it's unfamiliar to the audience.

"The terms pM0 and MX are not valid TNM categories. The following categories may be used:"

Line 46:39 · 'TNM' has no definition. Spell it out if it's unfamiliar to the audience.
Headings Case
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"Primary tumour (T)"

Line 4:5 · 'Primary tumour (T)' should use sentence-style capitalization.

"Regional lymph node (N)"

Line 43:5 · 'Regional lymph node (N)' should use sentence-style capitalization.

"Distant metastases (M)"

Line 45:5 · 'Distant metastases (M)' should use sentence-style capitalization.
List Caps
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"Tis: carcinoma in situ"

Line 7:16 · In general, we don't start a list item with a capital letter. Exceptions are proper nouns.

"T4a: moderately advanced local disease in which tumour invades any of the following:"

Line 21:12 · In general, we don't start a list item with a capital letter. Exceptions are proper nouns.

"T4b: very advanced local disease in which tumour encases carotid artery or invades any of the following:"

Line 31:12 · In general, we don't start a list item with a capital letter. Exceptions are proper nouns.

"Tis, N0, M0"

Line 57:12 · In general, we don't start a list item with a capital letter. Exceptions are proper nouns.

"T4a, [N0, N1], M0"

Line 77:8 · In general, we don't start a list item with a capital letter. Exceptions are proper nouns.

"T4b, [Any N], M0"

Line 85:8 · In general, we don't start a list item with a capital letter. Exceptions are proper nouns.
Colons
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"*Note: According to the AJCC 8th edition, involvement of the palatoglossus muscle within the oropharynx does not change the T category and this criterion mainly denotes invasion "anteriorly to the extrinsic muscles of the tongue in the floor of the mouth" 2."

Line 42:9 · The first word after a colon should almost always be lowercase. In this case, it's not: ': According to'.
Headings Valid
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Expected headings

  • H1 Terminology
  • H1 Usage
  • H1 Epidemiology
  • H2 Risk factors
  • H2 Associations
  • H1 Clinical presentation
  • H2 Complications
  • H1 Diagnosis
  • H2 Diagnostic criteria
  • H2 Diagnostic clues
  • H1 Pathology
  • H2 Aetiology
  • H2 Location
  • H2 Classification
  • H2 Macroscopic appearance
  • H2 Microscopic appearance
  • H2 Immunophenotype
  • H2 Markers
  • H2 Genetics
  • H1 Radiographic features
  • H2 Plain radiograph
  • H2 Mammography
  • H2 Antenatal ultrasound
  • H2 Transoesophageal echocardiography
  • H2 Ultrasound
  • H2 CT
  • H3 Dual-energy CT
  • H2 Angiography (DSA)
  • H2 MRI
  • H2 CT/MRI
  • H2 Nuclear medicine
  • H3 PET-CT
  • H3 PET-MRI
  • H1 Radiology report
  • H1 Treatment and prognosis
  • H2 Complications
  • H1 History and etymology
  • H1 Differential diagnosis
  • H2 Clinical differential diagnosis
  • H1 Practical points
  • H1 See also

"Staging"

Line 3:1 · "Staging" is not a recognised heading for this article type.

"Primary tumour (T)"

Line 4:1 · "Primary tumour (T)" is not a recognised heading for this article type.

"Regional lymph node (N)"

Line 43:1 · "Regional lymph node (N)" is not a recognised heading for this article type.

"Distant metastases (M)"

Line 45:1 · "Distant metastases (M)" is not a recognised heading for this article type.

"Stage groups"

Line 52:1 · "Stage groups" is not a recognised heading for this article type.

"Changes since prior versions"

Line 93:1 · "Changes since prior versions" is not a recognised heading for this article type.