"Post-radiation changes in the neck refer to a spectrum of anatomical and physiological alterations that occur following external beam radiation therapy, most commonly administered for head and neck malignancies, and often accompanied by preceding surgical resection of the primary tumour and neck dissection. These changes may affect skin, subcutaneous tissues, muscles, salivary glands, lymphatic structures, vessels, and bone, and can mimic or obscure recurrent disease on imaging 1,2."
"The management of post-radiation changes in the neck are generally supportive, including physical therapy and analgesia. Specific complications may require dedicated treatment (e.g. carotid stenosis, osteonecrosis)"
"Treatment and Prognosis"
Expected headings
"Early"
"Late"
"Pathophysiology"
"CT and MRI"
"Treatment and Prognosis"
"Post-radiation changes in the neck refer to a spectrum of anatomical and physiological alterations that occur following external beam radiation therapy, most commonly administered for head and neck malignancies, and often accompanied by preceding surgical resection of the primary tumour and neck dissection. These changes may affect skin, subcutaneous tissues, muscles, salivary glands, lymphatic structures, vessels, and bone, and can mimic or obscure recurrent disease on imaging 1,2."
"Radiation-induced changes are seen in the majority of patients undergoing curative or adjuvant radiotherapy for head and neck malignancies. The severity and extent are dose-dependent and also influenced by concurrent chemotherapy, immunotherapy and individual radiosensitivity 2."
"mucositis: painful oedema, ulceration and desquamation (very common)"
"early: oedema, swelling and enhancement"
"late: fistula formation (e.g. to pharynx)"
"The management of post-radiation changes in the neck are generally supportive, including physical therapy and analgesia. Specific complications may require dedicated treatment (e.g. carotid stenosis, osteonecrosis)"
"late: decreased size, fatty hilum prominence; post-treatment nodes can remain enlarged without active disease"