"In addition to the above features, it is recognised the posterior cortical atrophy can coexist with other neurodegenerative features (so called PCA-plus 8). These include:"
"Furthermore, a number of gene mutations have been identified in posterior cortical atrophy including presenilin 1 and 2 genes (PSEN1 and PSEN2), prion protein gene (PRNP), progranulin gene (GRN) and microtubule-associated protein tau gene (MAPT) 5,6."
"Parkinsonian symptoms later in the disease"
"Approximately 25% of patients with posterior cortical atrophy will also develop visual hallucinations 1,8. These patients may represent a distinct subgroup, with hallucinations believed to be due to the complex interplay between the midbrain, thalamus and primary visual cortex, rather than the visual association areas 1."
"Early in the course of the disease, insight and episodic memory are largely intact. As the disease progresses, however, more generalised cognitive impairment, including memory deficits, develops 8."
"The main findings are bilateral, but often more pronounced right-sided, parietal and parieto-occipital and temporo-occipital atrophy. Hippocampi are relatively normal. The parieto-occipital sulcus is reported to be wider in posterior cortical atrophy compared to Alzheimer disease 7."
"limb rigidity or akinesia, dystonia or myoclonus"
"Furthermore, a number of gene mutations have been identified in posterior cortical atrophy including presenilin 1 and 2 genes (PSEN1 and PSEN2), prion protein gene (PRNP), progranulin gene (GRN) and microtubule-associated protein tau gene (MAPT) 5,6."