"The reported incidence varies from 0.3-9.5% at autopsy or surgical biopsy and likely reflects the extent of sampling 4. They are absent from fetal and neonatal lung and are therefore acquired 7. DPM is ten times more common in women, with a median age of 60 years at presentation (range 30 - 80 years) 7. The nodules are commonly less than 2 mm in diameter and may escape detection by CT."
"They were originally called pulmonary chemodectomas, but further studies revealed meningothelial cells and an absence of endocrine granules 3,5."
Expected headings
"Immunohistochemistry"
"Diagnosis requires clinical, radiological and pathological correlation, disease stability and exclusion of metastatic meningioma."
"Histology demonstrates nests of perivenular and interstitial spindle-to-epithelioid cells with morphologic, ultrastructural and immunohistochemical profiles identical to meningiomas. Intracranial meningiomas and meningothelial nodules can display similar genetic alterations i.e. deletion of the NF2 gene and chromosomal gains of 22q."