"T1: isointense to grey matter"
"T2: hypointense to grey matter"
"T1 C+ (Gd): homogeneous enhancement"
"This condition was initially described by Juan Rosai (1940-2020) 16 and Ronald F Dorfman (1923-2012) 15 in 1969 3."
"The exact cause of sporadic Rosai-Dorfman disease is unknown but disordered immune regulation and viral infections (e.g. EBV, HHV) are thought to be involved 9."
"The exact cause of sporadic Rosai-Dorfman disease is unknown but disordered immune regulation and viral infections (e.g. EBV, HHV) are thought to be involved 9."
"Familial Rosai-Dorfman disease is due to mutations in SLC29A3."
"In individuals with intracranial involvement, headaches and seizures have been described and in many, no systemic manifestations are present 8,14. Additional site-specific signs and symptoms may also be present (e.g. pituitary dysfunction)."
"In individuals with intracranial involvement, headaches and seizures have been described and in many, no systemic manifestations are present 8,14. Additional site-specific signs and symptoms may also be present (e.g. pituitary dysfunction)."
"There is very wide distribution. The condition can affect a multitude of organ systems which include:"