"Immunohistochemistry is essential for their diagnosis, usually being positive for vimentin, S-100, EMA, galectin-3 and thyroid transcription factor 1 (TTF1) 2-3,5,6. Electronic microscopy will show swollen mitochondria, a reduced number of lysosomes, and rough endoplasmic reticulum 5."
"T1 C+ (Gd): intense heterogeneous early enhancement, in contradistinction to macroadenomas, which enhance more slowly and not as avidly 5"
"In the 5th edition (2021) of the WHO classification of CNS tumours, these tumours are grouped together with granular cell tumours of the pituitary and pituicytomas as "most likely representing a spectrum of a single nosological entity" unified by all having expression of thyroid transcription factor 1 (TTF-1) 6. Having said that, they go on to describe distinctive histological features, as such we continue to discuss these two other entities separately."
"Immunohistochemistry is essential for their diagnosis, usually being positive for vimentin, S-100, EMA, galectin-3 and thyroid transcription factor 1 (TTF1) 2-3,5,6. Electronic microscopy will show swollen mitochondria, a reduced number of lysosomes, and rough endoplasmic reticulum 5."
"T1/T2"
"isointense to the brain parenchyma on T1"
"T1 C+ (Gd): intense heterogeneous early enhancement, in contradistinction to macroadenomas, which enhance more slowly and not as avidly 5"
Expected headings
"Radiological features"
"CT"
"MRI"
"Immunohistochemistry is essential for their diagnosis, usually being positive for vimentin, S-100, EMA, galectin-3 and thyroid transcription factor 1 (TTF1) 2-3,5,6. Electronic microscopy will show swollen mitochondria, a reduced number of lysosomes, and rough endoplasmic reticulum 5."
"These tumours can be intrasellar, with or without a suprasellar component 2. Less frequently, they can invade the cavernous sinuses, destroy the sellar floor, and extend into the sphenoid sinus 2-4."
"History and etymology"