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Lint: splanchnic-vein-thrombosis

Oxford Comma
suggestion

"Most guidelines recommend Doppler ultrasound as the initial imaging modality to demonstrate vascular filling defects. However, CT and MRI are warranted to confirm the diagnosis, characterise the extent of thrombosis, and evaluate underlying pathologies 3,4. Additionally, despite its high sensitivity for ruling out splanchnic vein thrombosis, D-dimer testing remains controversial in this setting 5."

Line 3:122 · Use the Oxford comma in 'However, CT and MRI'.
Commas
suggestion

"While frequently discovered incidentally, acute splanchnic vein thrombosis primarily presents with abdominal pain, nausea, vomiting, anorexia, diarrhoea, and fever 3. However, because splanchnic vein thrombosis is predominantly a secondary complication, the overt symptoms of the precipitating illness frequently mask the localised signs of concurrent thrombosis ref."

Line 5:44 · More than 5 commas in a single sentence might make it more difficult to read.