"The standardised uptake value (SUV) applies to PET imaging of tumours and typically uses the radioligand F18-2-fluoro-2-deoxy-D-glucose (FDG). The concentration of F18 activity reflects glucose metabolism, which is increased in tumour cells and inflammation."
"FDG PET-CT is used to detect malignancy and measure treatment response; however, the values can be measured in different ways, such as ‘max’, ‘mean’ or ‘peak’ and are vulnerable to biological and technical sources of variation 7. Uptake values are sometimes normalised to lean body mass (LBM) or body surface area. However, body weight is the most commonly used because it is easy to calculate and is reproducible 7."
"SUV may be influenced by biological and technical factors such as blood glucose level, image noise, image resolution and variable region of interest selection. The cut-off between benign and malignant lesions is in the SUV range of 2.0-2.5; however, infectious and inflammatory conditions also demonstrate hypermetabolism. FDG PET sensitivity and specificity decrease with lesions"
"SUV may be influenced by biological and technical factors such as blood glucose level, image noise, image resolution and variable region of interest selection. The cut-off between benign and malignant lesions is in the SUV range of 2.0-2.5; however, infectious and inflammatory conditions also demonstrate hypermetabolism. FDG PET sensitivity and specificity decrease with lesions"