Radiopaedia Helpers

Units

error

"Technetium-99m pyrophosphate (Tc-99m PYP) is one of the technetium radiopharmaceuticals used primarily in the imaging diagnosis of transthyretin amyloidosis (ATTR) ¹. It can also be used to detect abnormalities in the areas of calcium deposition and damaged tissues such as bone, blood and heart ^2,3."

Line 1:12 · Put a space between the number and the unit in 'Technetium-99m'.

"physical half-life: ~6hours"

Line 6:29 · Put a space between the number and the unit in '6h'.

"dose: ^99mTc-PYP: 370-640 MBq intravenously"

Line 30:19 · Put a space between the number and the unit in '99mTc'.

"uptake time ^99mTc-PYP only: 1 hour"

Line 33:21 · Put a space between the number and the unit in '99mTc'.

"Technetium-99m is a metastable nuclear isomer with favourable gamma emission properties, thus it is frequently used in nuclear medicine."

Line 54:12 · Put a space between the number and the unit in 'Technetium-99m'.

Strong List Colon Position

error

"Transthyretin amyloidosis - Primary use ⁷:"

Line 28:4 · When enboldening an intro, the colon should not be bold. 'Transthyretin amyloidosis - Primary use 7:'

"Detection of acute myocardial infarction - historical use ²:"

Line 41:4 · When enboldening an intro, the colon should not be bold. 'Detection of acute myocardial infarction - historical use 2:'

"Bone imaging - historical use ³:"

Line 46:4 · When enboldening an intro, the colon should not be bold. 'Bone imaging - historical use 3:'

Isotope Notation

error

"dose: ^99mTc-PYP: 370-640 MBq intravenously"

Line 30:19 · Write the isotope as symbol-mass, e.g. F-18, not '99mTc'.

"uptake time ^99mTc-PYP only: 1 hour"

Line 33:21 · Write the isotope as symbol-mass, e.g. F-18, not '99mTc'.

Hybrid Imaging Slash

error

"CT attentuation correction: heart recommended. SPECT/CT fusion is helpful in localising tracer uptake to the myocardium"

Line 37:51 · Hybrid imaging takes a hyphen, not a slash: 'SPECT/CT'.

Number Spacing

error

"within 24- 72 hours post event"

Line 43:15 · In a number range, there should not be spaces around the hyphen ('24- 72').

List Punctuation

error

"Technetium-99m is a metastable nuclear isomer with favourable gamma emission properties, thus it is frequently used in nuclear medicine."

Line 54:144 · Do not put full stops at the end of a list item.

"Pyrophosphate is a ligand containing two phosphate groups and a high affinity for calcium-rich environments. It is chelated to technetium-99m."

Line 55:135 · Do not put full stops at the end of a list item.

Acronyms

warning

"Technetium-99m pyrophosphate (Tc-99m PYP) is one of the technetium radiopharmaceuticals used primarily in the imaging diagnosis of transthyretin amyloidosis (ATTR) ¹. It can also be used to detect abnormalities in the areas of calcium deposition and damaged tissues such as bone, blood and heart ^2,3."

Line 1:49 · 'PYP' has no definition. Spell it out if it's unfamiliar to the audience.

"Technetium-99m pyrophosphate (Tc-99m PYP) is one of the technetium radiopharmaceuticals used primarily in the imaging diagnosis of transthyretin amyloidosis (ATTR) ¹. It can also be used to detect abnormalities in the areas of calcium deposition and damaged tissues such as bone, blood and heart ^2,3."

Line 1:193 · 'ATTR' has no definition. Spell it out if it's unfamiliar to the audience.

"it has a high affinity for extracellular amyloid deposits (i.e. those found in ATTR) ⁶"

Line 15:87 · 'ATTR' has no definition. Spell it out if it's unfamiliar to the audience.

"dose: ^99mTc-PYP: 370-640 MBq intravenously"

Line 30:31 · 'PYP' has no definition. Spell it out if it's unfamiliar to the audience.

"uptake time ^99mTc-PYP only: 1 hour"

Line 33:33 · 'PYP' has no definition. Spell it out if it's unfamiliar to the audience.

"Tc-99m PYP was first curated in the mid 1970s and was one of the first radiotracers used to image acute myocardial infarctions ². With advances in medicine, it was replaced by more specific tests such as troponin. Tc-99m PYP was discovered to have a high affinity for transthyretin amyoid in mid-2000 resulting in the adoption for non-invasive diagnosis of ATTR ¹."

Line 52:11 · 'PYP' has no definition. Spell it out if it's unfamiliar to the audience.

"Tc-99m PYP was first curated in the mid 1970s and was one of the first radiotracers used to image acute myocardial infarctions ². With advances in medicine, it was replaced by more specific tests such as troponin. Tc-99m PYP was discovered to have a high affinity for transthyretin amyoid in mid-2000 resulting in the adoption for non-invasive diagnosis of ATTR ¹."

Line 52:236 · 'PYP' has no definition. Spell it out if it's unfamiliar to the audience.

"Tc-99m PYP was first curated in the mid 1970s and was one of the first radiotracers used to image acute myocardial infarctions ². With advances in medicine, it was replaced by more specific tests such as troponin. Tc-99m PYP was discovered to have a high affinity for transthyretin amyoid in mid-2000 resulting in the adoption for non-invasive diagnosis of ATTR ¹."

Line 52:372 · 'ATTR' has no definition. Spell it out if it's unfamiliar to the audience.

Strong

warning

"Transthyretin amyloidosis - Primary use ⁷:"

Line 28:4 · Generally, don't use bold in text: 'Transthyretin amyloidosis - Primary use 7:'

"Detection of acute myocardial infarction - historical use ²:"

Line 41:4 · Generally, don't use bold in text: 'Detection of acute myocardial infarction - historical use 2:'

"Bone imaging - historical use ³:"

Line 46:4 · Generally, don't use bold in text: 'Bone imaging - historical use 3:'

Emphasis

warning

"Technetium-99m is a metastable nuclear isomer with favourable gamma emission properties, thus it is frequently used in nuclear medicine."

Line 54:8 · Italics should be used only in exceptional circumstances: 'Technetium-99m'

List Caps

warning

"Technetium-99m is a metastable nuclear isomer with favourable gamma emission properties, thus it is frequently used in nuclear medicine."

Line 54:12 · In general, we don't start a list item with a capital letter. Exceptions are proper nouns.

Headings Valid

warning

Expected headings

H1 Terminology
H1 Usage
H1 Epidemiology
H2 Risk factors
H2 Associations
H1 Clinical presentation
H2 Complications
H1 Diagnosis
H2 Diagnostic criteria
H2 Diagnostic clues
H1 Pathology
H2 Aetiology
H2 Location
H2 Classification
H2 Macroscopic appearance
H2 Microscopic appearance
H2 Immunophenotype
H2 Markers
H2 Genetics
H1 Radiographic features
H2 Plain radiograph
H2 Mammography
H2 Antenatal ultrasound
H2 Transoesophageal echocardiography
H2 Ultrasound
H2 CT
H3 Dual-energy CT
H2 Angiography (DSA)
H2 MRI
H2 CT/MRI
H2 Nuclear medicine
H3 PET-CT
H3 PET-MRI
H1 Radiology report
H1 Treatment and prognosis
H2 Complications
H1 History and etymology
H1 Differential diagnosis
H2 Clinical differential diagnosis
H1 Practical points
H1 See also

"Characteristics"

Line 2:1 · "Characteristics" is not a recognised heading for this article type.

"Uses, doses and timings"

Line 27:1 · "Uses, doses and timings" is not a recognised heading for this article type.

Oxford Comma

suggestion

"Technetium-99m pyrophosphate (Tc-99m PYP) is one of the technetium radiopharmaceuticals used primarily in the imaging diagnosis of transthyretin amyloidosis (ATTR) ¹. It can also be used to detect abnormalities in the areas of calcium deposition and damaged tissues such as bone, blood and heart ^2,3."

Line 1:320 · Use the Oxford comma in 'bone, blood and heart'.

"Uses, doses and timings"

Line 27:5 · Use the Oxford comma in 'Uses, doses and timings'.

Inline EG

suggestion

"increased tracer uptake in areas of increased osteogenesis or bone growth (e.g. fractures)"

Line 48:78 · Consider replacing a bracketed e.g. with an inline e.g. after a comma.

Lint: technetium-99m-pyrophosphate