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Lint: triple-receptor-negative-breast-cancer

Spacing
error

"TRN cancers were more frequently presented mammographically as a round, oval, or lobulated mass and were less frequently associated with calcifications than HER2+ / ER+ cancers. Less likely to demonstrate typical characteristics of malignancy, such as an irregular shape or spiculated margins 12. Associated ductal carcinoma in situ (DCIS) has also been reported at a much lower rate than HER2+, and ER+ patients."

Line 17:179 · 's. L' should have one space.
Strong List Colon Position
error

"T2 with fat suppression: intratumoural hyperintensity is common corresponds to abundant cytoplasm, oedematous stroma and necrosis 11"

Line 30:1 · When enboldening an intro, the colon should not be bold. '<strong>T2 with fat suppression:</strong> intratumoural'

"T1C+: rim enhancement is a specific sign that helps to differentiate small TRN breast cancers from benign lesions like fibroadenoma 11"

Line 33:1 · When enboldening an intro, the colon should not be bold. '<strong>T1C+:</strong> rim'
Acronyms
warning

"TRN cancers were more frequently presented mammographically as a round, oval, or lobulated mass and were less frequently associated with calcifications than HER2+ / ER+ cancers. Less likely to demonstrate typical characteristics of malignancy, such as an irregular shape or spiculated margins 12. Associated ductal carcinoma in situ (DCIS) has also been reported at a much lower rate than HER2+, and ER+ patients."

Line 17:169 · 'ER' has no definition. Spell it out if it's unfamiliar to the audience.

"TRN cancers were more frequently presented mammographically as a round, oval, or lobulated mass and were less frequently associated with calcifications than HER2+ / ER+ cancers. Less likely to demonstrate typical characteristics of malignancy, such as an irregular shape or spiculated margins 12. Associated ductal carcinoma in situ (DCIS) has also been reported at a much lower rate than HER2+, and ER+ patients."

Line 17:423 · 'ER' has no definition. Spell it out if it's unfamiliar to the audience.

"Due to the absence of hormone receptors and HER-2, treatments like hormone therapy and other drugs which target oestrogen, progesterone and HER-2 are ineffective. However, chemotherapy is considered to be an effective option in such cases with it responding earlier and better as compared to other breast malignancies."

Line 37:48 · 'HER' has no definition. Spell it out if it's unfamiliar to the audience.

"Due to the absence of hormone receptors and HER-2, treatments like hormone therapy and other drugs which target oestrogen, progesterone and HER-2 are ineffective. However, chemotherapy is considered to be an effective option in such cases with it responding earlier and better as compared to other breast malignancies."

Line 37:144 · 'HER' has no definition. Spell it out if it's unfamiliar to the audience.
Strong
warning

"T2 with fat suppression: intratumoural hyperintensity is common corresponds to abundant cytoplasm, oedematous stroma and necrosis 11"

Line 30:1 · Generally, don't use bold in text: '<strong>T2 with fat suppression:</strong>'

"T1C+: rim enhancement is a specific sign that helps to differentiate small TRN breast cancers from benign lesions like fibroadenoma 11"

Line 33:1 · Generally, don't use bold in text: '<strong>T1C+:</strong>'
Commas
suggestion

"They have distinctive pathologic features, typically exhibiting a higher histologic grade, elevated mitotic count, central necrosis and fibrosis, pushing margins, scant stromal reaction, stromal lymphocytic response, and ductal or mixed histology with an overrepresentation of unusual histologies (metaplastic, medullary, or adenoid cystic carcinoma). It comprises of a heterogeneous group, encompassing at least two subcategories:"

Line 10:45 · More than 5 commas in a single sentence might make it more difficult to read.
Oxford Comma
suggestion

"Due to the absence of hormone receptors and HER-2, treatments like hormone therapy and other drugs which target oestrogen, progesterone and HER-2 are ineffective. However, chemotherapy is considered to be an effective option in such cases with it responding earlier and better as compared to other breast malignancies."

Line 37:116 · Use the Oxford comma in 'oestrogen, progesterone and HER'.