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Lint: undifferentiated-spondyloarthritis-1

Prefix Hyphens
warning

"Back pain, enthesitis, and peripheral arthritis are common, as well as extra-skeletal manifestations such as dactylitis and fatigue 1."

Line 5:82 · A prefix takes a hyphen only to avoid a duplicate letter: 'extra-skeletal'.
Acronyms
warning

"Only 50% of presentations have abnormal levels of acute-phase reactants (CRP, ESR), and only 10% are positive for rheumatoid factor despite many eventually declaring themselves as rheumatoid arthritis 3."

Line 21:82 · 'ESR' has no definition. Spell it out if it's unfamiliar to the audience.
Oxford Comma
suggestion

"Undifferentiated spondyloarthritis (uSpA), also known as undifferentiated arthritis, is a non-specific mono- or polyarthropathy that lacks the clinical, serological and radiological features that would allow specific diagnosis. It often turns out to be an early presentation of a more well-known form of arthritis."

Line 1:198 · Use the Oxford comma in 'clinical, serological and radiological'.