"The antimicrobial drug class, the sulfonamides, inhibit dihydropteroate synthetase, the enzyme which forms folic acid from para-aminobenzoic acid (PABA). This reaction does not occur in mammalian cells, hence does not affect human DNA synthesis and is specific for microbes."
"The chemotherapeutic methotrexate inhibits dihydrofolate reductase which converts folate into its active form tetrohydrofolic acid (THF)."
"The antimicrobial drug class, the sulfonamides, inhibit dihydropteroate synthetase, the enzyme which forms folic acid from para-aminobenzoic acid (PABA). This reaction does not occur in mammalian cells, hence does not affect human DNA synthesis and is specific for microbes."
Expected headings
"Related pathology"