"It is named after Erik Adolf von Willebrand (1870-1949), Finnish physician and medical professor, who first described this condition in 1926 after studying a family on the Aland islands affected by a bleeding disorder 3. Interestingly he also published on the medicinal benefits of the sauna."
"von Willebrand disease does not have a specific appearance on imaging studies. It can be considered in a setting of unexplained haemorrhage."
"There are multiple forms of the disease, but bleeding is most often due to an autosomal dominant disorder affecting factor VIII, von Willebrand factor, or both. The lack of this factor leads to decreased platelet activation. Acquired forms of the disease are caused by autoantibodies targeting von Willebrand factor."