"There are different pathological mechanisms depicted in literature, few of them includes irritation of the nerve pathway from the vulva to the spinal cord. The surge of inflammatory markers like cytokines, genetic vulnerability and pelvic floor muscle instability and weakness."
"Multimodality approach with avoidance of irritating factors, tricyclic antidepressants, antiseizure medications, local pain-relieving drugs, pelvic floor strengthens exercises, physiotherapy, nerve block and sometimes surgical methods are employed to relieve symptoms."