"Following vertical transmission to the fetus, Zika virus infection manifests as microcephaly most commonly, and a spectrum of congenital structural and functional abnormalities known as congenital Zika syndrome11."
"Zika is a single-stranded RNA flavivirus 7. It can be transmitted via vector or non-vector-borne routes. For vector transmission, it is transmitted through a bite by an infected mosquito of the Aedes species, commonly Aedes aegypti and Aedes albopictus 8. Non-vector-borne routes include sexual contact, vertical transmission from mother to child during intrauterine or intrapartum period, and via blood transfusion or organ/tissue transplantation 3,9."
"Congenital Zika vial infection has been shown to cause various brain abnormalities affecting both grey and white matter and ventricular size 4,5. Intracranial calcifications resulting from congenital Zika virus infections are typically more florid than caused by the TORCH infections and also characteristically at the grey-white matter interface, which is unusual for other congenital viral diseases."
"Zika is a single-stranded RNA flavivirus 7. It can be transmitted via vector or non-vector-borne routes. For vector transmission, it is transmitted through a bite by an infected mosquito of the Aedes species, commonly Aedes aegypti and Aedes albopictus 8. Non-vector-borne routes include sexual contact, vertical transmission from mother to child during intrauterine or intrapartum period, and via blood transfusion or organ/tissue transplantation 3,9."
"Congenital Zika virus infection"
"Adult Zika virus infection"
Expected headings
"Congenital Zika virus infection"
"Adult Zika virus infection"
"In the majority of adult cases including pregnant women, Zika virus infections are asymptomatic 7,11.When symptoms are present in adults, they are usually mild, with a similar presentation to dengue and chikungunya fever, such as fever, malaise, joint pain, conjunctivitis and rash 7. Nervous system involvement from Zika virus infections has also been described. These are commonly associated with Guillain-Barré syndrome, and less commonly with encephalitis, meningitis, and myelitis 7,10."
"In the majority of adult cases including pregnant women, Zika virus infections are asymptomatic 7,11.When symptoms are present in adults, they are usually mild, with a similar presentation to dengue and chikungunya fever, such as fever, malaise, joint pain, conjunctivitis and rash 7. Nervous system involvement from Zika virus infections has also been described. These are commonly associated with Guillain-Barré syndrome, and less commonly with encephalitis, meningitis, and myelitis 7,10."
"Radiographic features of congenital Zika viral infection have been reported on ultrasound, CT and MRI, and most result from a negative effect on brain development."
"Most Zika virus infections are self-limited, with only supportive treatment required if complications arise 7. Preventative measures and early detection are the most important principles in reducing risks of congenital Zika syndrome 11. Vaccines against Zika virus are currently under clinical trial 13."