"history of recurrent fractures and/or pseudofractures ~ 40% 1"
Line 5:66·No space after an approximation symbol: '~ 4'.
Acronyms
warning
"A reduced enzymatic activity of alkaline phosphatase (ALP) is the key marker of the disease, causing an accumulation of ALP substrates such as pyridoxal-5-phosphate (PLP)."
Line 22:177·'PLP' has no definition. Spell it out if it's unfamiliar to the audience.