"These tumours affect females more than males, as it is commonly associated with post-mastectomy lymphoedema. The incidence is unknown, but studies have shown that it has occurred in ~0.25% (range 0.03-0.45%) of patients who survive at least 5 years after radical mastectomy 6,7."
"This is a poor prognostic tumour, the mean survival rate is ~ 2 years with a 5-year survival rate of ~20% 12. The treatment is aggressive surgical resection and amputation of limbs is frequently recommended, even though the recurrence rate still high ref."
"Chronic lymphoedema-associated angiosarcoma is used in the WHO Soft Tissue and Bone Tumours (5th ed.); lymphangiosarcoma is not a recommended term 5."
"Chronic lymphoedema-associated angiosarcoma is used in the WHO Soft Tissue and Bone Tumours (5th ed.); lymphangiosarcoma is not a recommended term 5."
"The occurrence of angiosarcoma in patients with chronic lymphoedema post radical mastectomy was first reported by American pathologist FW Stewart (1894-1991) and American surgeon N Treves (d. 1964) in 1948 13-15."
Expected headings
"Signal characteristics"
"Chronic lymphoedema-associated angiosarcoma is used in the WHO Soft Tissue and Bone Tumours (5th ed.); lymphangiosarcoma is not a recommended term 5."
"Chronic lymphoedema-associated angiosarcomas was first associated with lymphoedema secondary to radical mastectomy to treat breast cancer 13; however, it has been shown to arise in chronically lymphoedematous regions of any cause 8. Chronic lymphoedema seems to induce a degree of local immunodeficiency that leads to oncogenesis 9."
"History and etymology"