"T1: intermediate to high intensity"
"T2: heterogeneously high signal intensity"
"T1 C+ (Gd): heterogeneous enhancement"
"CIC-rearranged sarcomas or CIC-DUX4 sarcomas are aggressive undifferentiated small round cell sarcomas with CIC gene fusions, most frequently CIC-DUX4. It is an ultra-rare high-grade undifferentiated sarcoma, distinct in terms of clinical presentations and molecular characteristics 6."
"Immunohistochemistry stains show a mostly patchy and less commonly diffuse and membranous CD99 expression with additional positivity of WT1 and ETV4 in >90%. NKX2-2 is typically negative. NUT protein might be positive in sarcomas with CIC-NUTM1 fusions 1,2."
"Approximately 95% of CIC-rearranged sarcomas are characterised by CIC-DUX4 gene fusions. The remainder includes the involvement of partner genes as FOXOE4, LEUTX, NUTM1 and NUTM2a 1-4."
"Immunohistochemistry stains show a mostly patchy and less commonly diffuse and membranous CD99 expression with additional positivity of WT1 and ETV4 in >90%. NKX2-2 is typically negative. NUT protein might be positive in sarcomas with CIC-NUTM1 fusions 1,2."
"Approximately 95% of CIC-rearranged sarcomas are characterised by CIC-DUX4 gene fusions. The remainder includes the involvement of partner genes as FOXOE4, LEUTX, NUTM1 and NUTM2a 1-4."